Medications for Leukaemia

Chronic lymphocytic leukemia is usually treated with Chlorambucil (alkylating agent) and fludarabine (antimetabolite). Also fludarabine as well as Purine analogues have proven to be very useful in its treatment. A significant number of patients have experienced remission after using fludarabine. Upon exposure it has appeared to induce apoptosis in lymphocytes that are malignant. Used in a combination with cyclophosphamide (FC) it has shown better results than when used alone. Its combination with alemtuzumab and rituximab is expected to be more effective. Alemtuzumab importance in the eradication of MRD is also being researched.